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Thioredoxin has also been shown to bind to ASK1 to inhibit its activity like a kinase [32]. This inhibition is attenuated by ROS that can lead to dimerization of thioredoxin [33]. Thioredoxin regulation on the glucocorticoid receptor through Affiliation on the DNA binding area has also been documented [34] which too is motivated by ROS. Much more n
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